LIVING WITH BRCA MUTATIONS: FAMILY COMMUNICATION AND REPRODUCTIVE CHOICES
A. Romeo, S.Petruzzello, V. Russello, S. Rametta Giuliano, M.C. Careri, E. Tata, I. Vinci Mortillaro, A. Elia
Vol.9 issue 1 (2026), pag. 16 - 24
| Received | 22/09/2025 |
| Accepted | 17/02/2026 |
| Published | 9/03/2026 |
| Review by | Single-blind |
| doi | https://doi.org/10.48252/JCR118 |
ABSTRACT
Breast cancer is a multifactorial disease with a significant genetic component, particularly related to BRCA1/2 mutations, which markedly increase the risk of breast and ovarian cancers. The identification of a pathogenic variants carries clinical, preventive, and psychological implications, that extend to family members. Oncogenetic counseling plays a central role in identifying at-risk individuals, guiding decision-making, and supporting psychological well-being. This article explores the communication of the diagnosis within families, coping with cancer risk, and fertility management in young women.