INVESTIGATION OF FACTORS RELATED TO REDUCED SCORES ON THE SHORT PHYSICAL PERFORMANCE BATTERY OF PATIENTS WITH ADVANCED OR RECURRENT SOLID TUMORS
M. Kusaba, M. Sunahara, T. Fukushima, J. Nakano, T. Ebisu, K. Yanagihara
Vol.7 issue 1 (2024), pag. 16 - 22
| Received | 19/01/2024 |
| Accepted | 6/02/2024 |
| Published | 27/02/2024 |
| Review by | Double-blind |
| doi | https://doi.org/10.48252/JCR92 |
ABSTRACT
Background
This study aimed to investigate the factors associated with reduced short physical performance battery (SPPB) scores in patients with advanced or recurrent solid tumors.
Materials and Methods
This cross-sectional observational study was conducted at the Kansai Electric Power Hospital. We recruited patients who had received chemotherapy or radiotherapy. At the start of rehabilitation, we evaluated lower limb muscle strength (motricity index), physical function (SPPB), physical activity (International Physical Activity Questionnaire), symptoms (Edmonton Symptom Assessment System Revised Japanese version), and the modified Glasgow prognostic score (mGPS). Univariate logistic regression analysis was performed to investigate the factors associated with reduced SPPB scores, and multivariate logistic regression analysis was performed for items with significant differences.
Results
Seventy-one patients were included in this study. Univariate logistic regression analysis revealed that age, history of surgery, history of chemotherapy, physical activity, muscle strength, pain, lack of appetite, and mGPS were factors associated with reduced SPPB scores. A history of surgery, physical activity, and muscle strength were independent factors associated with reduced SPPB scores in the multivariate logistic regression analysis.
Conclusions
Muscle strength, physical activity, and history of surgery influence the decline in physical function. Even in advanced or recurrent cases, interventions that focus on physical activity and muscle strength are required.