Palliative chemotherapy and targeted agents in elderly patients with advanced gastric cancer
A. Colombo, C.M. Porretto
Vol.6 (2021), issue 2, pag. 91 - 99
| Received | 5/08/2021 |
| Accepted | 29/09/2021 |
| Published | 14/10/2021 |
| Review by | Single-blind |
| DOI | https://doi.org/10.48253/AGO15 |
ABSTRACT
Gastric cancer in the elderly represents a distinct entity with spe- ci c clinicopathological characteristics and the majority of affected patients belong to this age group. Subtotal or total gastrectomy with radical lymph node dissection, adjuvant chemo-radiotherapy or pe- rioperative chemotherapy represent the only potentially curative treatment options and seem to be performed with acceptable mor- bidity and mortality rates in selected elderly patients.
In the advanced or metastatic phase, the only strategies available are chemotherapy, targeted agents and immunotherapy with palli- ative purposes.