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Submission To Be Reviewed

Title: Unemployment risk and income change following a brain tumor diagnosis: A population-based study of long-term survivors

Journal Section


Background: There is paucity of data regarding unemployment and income change following a brain tumor diagnosis among adults. We aimed to examine the risks for unemployment and decreased income at 2 and 4 years after brain tumor diagnosis.

Methods: Baseline measurements for this study were obtained from the Israeli Central Bureau of Statistics 1995 National Census, which was followed-up until 2011 (a median follow up of 7.4 years), and cancer incidence from the Israel Cancer Registry. Patients who died before the end of 2011 were excluded from the study. Only patients between the ages of 15-60 years, at the time of interview (1995) were included (n=377). The matched group includes a 3:1 ratio based on age, sex, and ethnicity (n=1001).

Results:  An increased risk for unemployment was found in brain tumor survivors at 2 and 4 years after the diagnosis (P < .001 and P < .001, respectively). This association was found in all brain tumor subtypes, including meningioma survivors (n=249) at 2 and 4 years after diagnosis (P = .009 and P = .004, respectively). Furthermore, brain tumor patients were also associated with a decrease in income at 2 and 4 years after diagnosis (P < .001 and P < .001, respectively). 

Conclusion(s):  Long-term brain tumor survivors are at increased risk for unemployment and decrease income. This study highlights the need for more effective strategies to enhance re-employment and establish focused rehabilitation programs.

Keywords: central nervous system tumors; cancer survivors; employment. 

Review Schedule

Editor's request 17-05-2018

Your Response 

Review Submitted 

Review Due 


1) Does this paper present new ideas or results that have not been previously published? 2) Is the research presented in the article new or build upon existing research? 3) Does the article point out differences from related research?
Does the article make a considerable contribution to the oncology field?
1) Does the title clearly express the content of the article? Is 2) Is the abstract sufficiently informative and provides a good perspective on the final message of the aricle?
1) Are the methods used clearly explained? 2) Are they a recognized approach? 3) Are the data and statistics used reliable?
1) Are they clearly presented? 2) Do they avoid misinterpretation? 3) Do they sufficiently avoid assumptions and speculations?
1) Do they reflect the latest research in the area? 2) Are they correctly indicated in article? 3) Are they correctly formatted according to the author guidelines?
1) Are the tables correctly name and numbered? 2) Are the data presented in the table correctly interpreted in the article?
1) Are the figures correctly named and numbered? 2) Do they properly illustrate what is discussed in the article? 3) Are they correctly interpreted in the article?
1) Is the article clearly written?
1) Does the article fit the guidelines for the section as outlined in the instructions to authors?
Please rate the article in priority for publication based on the interest to our readership and contribution to the oncology field. (5) Being of hieghest priority and (1) being the lowest.