CONFRONTO DI PREVALENZA DELLE NEOPLASIE COLORETTALI IN DUE GRUPPI DI ETÁ IN UN PROGRAMMA DI SCREENING
G. Inserra, G. Riguccio, G. Bertino, L. Zanoli
Vol.3 (2018), issue 2, pag. 17-23

Received 18/04/2018
Accepted after revision 29/06/2018
Published June 2018
Review by Single-blind
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Background and aims
Colorectal cancer (CRC) has a high incidence and prevalence in Italy, as in other Western countries. Screening programs aim to reduce CRC mortality and incidence and their efficacy has been proven. Some uncertainty remains about the cost-effectiveness of screening in older age. We investigated the difference in prevalence of benign and malign colorectal neoplasia in a population undergoing a screening program in Sicily.
Methods We retrospectively analyzed the endoscopic and pathological reports of 5318 colonscopies performed on 2501 patients, adherent to a oncological screening program, from 1992 to 2008. All were workers of a chemical industry, living in various sites of eastern Sicily. The subjectes were diveded in two groups, one with less than 65 years of age and the other with age over 65 years.
Results The first group (under 65) consisted in 2424 patients, the second one (over 65) in 77 patients. Hyperplastic polyps were diagnosicated in 33% of patients in the first group versus 41.6% in the second one (p=0.12,ns). Adenomatous polyps in 16.1% versus 13% (p=0.46, ns). CRC patients were 0.8% in the younger group and 1.3% in the older one (p=0.25, ns).
Conclusions The results from an endoscopic database of a CRC screening program performed in Sicily we found no significative difference in the prevalence of colorectal neoplasia among subjects aged less than 65 years compared with subjects older than 65.